" In men younger than 40 years old, the number of excess myocarditis events per million people was higher after a second dose of mRNA-1273 than after a positive SARS-CoV-2 test (97 [95% CI, 91–99] versus 16 [95% CI, 12–18]). In women younger than 40 years, the number of excess events per million was similar after a second dose of mRNA-1273 and a positive test (7 [95% CI, 1–9] versus 8 [95% CI, 6–8])."
In this study ratio for <M40yo was larger by factor of 6x post vaccination vs post covid...
I forgot about two large biases and will update text accordingly in a few days.
"Athletic bias" post viral exercise that is physically strenuous is no no, not just in case of covid, but nature of these students is to be athletic and exercise, it is also reason of their admission, so likelihood of athlete to have heart problem because of their post viral behavior is increased, how much, 2x...5x? i don't know, if someone can untangle this bias, please comment. This bias direction is forward to increase incidence of heart related problems in this study in comparison to normal student population.
Another bias is in Thai study, parents of kids involved were more vaccine friendly, plus once you make decision to vaccinate your kid, likelihood of reporting problems that will counter your previous decision is smaller, this bias is also known as https://en.wikipedia.org/wiki/Escalation_of_commitment.
So focusing on troponin only for comparison purposes makes most sense. Even though in the study there was more reported issues (22 cases of arrhythmia 20 cases of tachycardia etc. details in table 4) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414075/
https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.122.059970
" In men younger than 40 years old, the number of excess myocarditis events per million people was higher after a second dose of mRNA-1273 than after a positive SARS-CoV-2 test (97 [95% CI, 91–99] versus 16 [95% CI, 12–18]). In women younger than 40 years, the number of excess events per million was similar after a second dose of mRNA-1273 and a positive test (7 [95% CI, 1–9] versus 8 [95% CI, 6–8])."
In this study ratio for <M40yo was larger by factor of 6x post vaccination vs post covid...
I forgot about two large biases and will update text accordingly in a few days.
"Athletic bias" post viral exercise that is physically strenuous is no no, not just in case of covid, but nature of these students is to be athletic and exercise, it is also reason of their admission, so likelihood of athlete to have heart problem because of their post viral behavior is increased, how much, 2x...5x? i don't know, if someone can untangle this bias, please comment. This bias direction is forward to increase incidence of heart related problems in this study in comparison to normal student population.
Another bias is in Thai study, parents of kids involved were more vaccine friendly, plus once you make decision to vaccinate your kid, likelihood of reporting problems that will counter your previous decision is smaller, this bias is also known as https://en.wikipedia.org/wiki/Escalation_of_commitment.
So focusing on troponin only for comparison purposes makes most sense. Even though in the study there was more reported issues (22 cases of arrhythmia 20 cases of tachycardia etc. details in table 4) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414075/